Host resistance to intranasalAcinetobacter baumanniireinfection in mice
نویسندگان
چکیده
منابع مشابه
Host resistance to ectoparasites.
Examples of immunological reactions to arthropod parasites include responses by hosts to the following stimuli: excretory and secretory antigens produced by myiasis-producing larvae or skin-dwelling (mange) mites salivary antigens of blood-sucking arthropods. In many cases, these are hypersensitivity reactions, which often appear not to produce very deleterious effects on the parasites. However...
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Acute graft-versus-host disease (GVHD) is characterized by the production of high levels of T helper 1 (Th1)-type cytokines. Bone marrow transplantation from allogeneic C57BL/6 cells to CBF(1) mice produced acute GVHD. Host resistance to Th1-driven Listeria monocytogenes was enhanced, whereas host resistance to Th2-driven Staphylococcus aureus was reduced during acute GVHD. These results sugges...
متن کاملApproaches to assessing host resistance.
There is increasing evidence that chronic, subclinical exposure to certain environmental pollutants may upset immune responsiveness and alter susceptibility of animals to infectious agents. Environmental chemicals or drugs may affect diverse aspects of the immune system, leading to immunosuppression, immunopotentiation, hypersensitivity or perturbed innate host resistance. A variety of infectio...
متن کاملAn important role of prostanoid receptor EP2 in host resistance to Mycobacterium tuberculosis infection in mice.
Mycobacterium tuberculosis, the causative agent of tuberculosis, resides and replicates within susceptible hosts by inhibiting host antimicrobial mechanisms. Prostaglandin E(2) (PGE(2)), produced by M. tuberculosis-infected macrophages, exerts a variety of immunomodulatory functions via 4 receptors (EP1-EP4), each mediating distinct PGE(2) functions. Here, we show that M. tuberculosis infection...
متن کاملNeutrophils play an important role in host resistance to respiratory infection with Acinetobacter baumannii in mice.
Acinetobacter baumannii has emerged as a major cause of both community-associated and nosocomial pneumonia, but little is known about the cellular and molecular mechanisms of host defense against respiratory infection with this bacterial pathogen. In this study, we examined the role of neutrophils in host resistance to pulmonary A. baumannii infection in a mouse model of intranasal (i.n.) infec...
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ژورنال
عنوان ژورنال: Pathogens and Disease
سال: 2016
ISSN: 2049-632X,2049-632X
DOI: 10.1093/femspd/ftw048